Flotillin complex

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August undefined, 2024

WebFlotillin-1 Antibody (C-2) is a mouse monoclonal IgG 1 κ Flotillin-1 antibody, cited in 49 publications, provided at 200 µg/ml; ... Flotillins form a ternary complex with CAP and Cbl, directing the localization of the CAP-Cbl complex to a lipid raft subdomain of the plasma membrane. Association of ER-X with Flotillin localizes ER-X within ...

Frontiers Case Report: Anti-flotillin 1/2 Autoantibody …

WebAutoantibodies might interfere with the flotillin 1/2 complex and counteract axonal integrity due to the function of flotillin proteins in axon growth (10, 11). Anti-flotillin-1/2 complex autoantibodies were identified in patients with multiple sclerosis ( 12 ), but until now, not in patients with severe cognitive impairment. WebOct 20, 2024 · d, e Interaction networks of the V-ATPase (d) and the flotillin (e) complex. f Co-IP of ATP6V1D and FZD9 (n = 2). ATP6V1B2 and ATP6V1A1 are known members of the V-ATPase complex; LAMP2 is a ... binning pronunciation

Exploring functional membrane microdomains in bacteria: an …

WebFlotillin-mediated endocytosis and ALIX–syntenin-1–mediated exocytosis protect the cell membrane from damage caused by necroptosis Weiliang Fan1,2, ... for the cross-linking and tandem affinity purification of the lipid raft–bound phospho-MLKL protein complex. TSZ, TNF (20 ng/ml), Smac mimetic (100 M), and z-VAD (20 M); DSP, dithiobis ... WebJul 20, 2024 · To the best of our knowledge, this is the first report showing molecular details underlying formation of the MPP1-flotillin complex that opens a new outlook in our … WebA protein complex that contains flotillin-1 and flotillin-2, and may contain associated proteins. Flotillins associate into membrane microdomains resembling caveolae. Source: … binning python code

Research Brief: Flotillin, Cholesterol Aid APP Endocytosis

Flot2 (flotillin 2) - Rat Genome Database - Medical College of …

WebDec 1, 2011 · Flotillins have been implicated in myriad processes that include endocytosis, signal transduction and regulation of the cortical cytoskeleton, yet the molecular … WebJun 23, 2024 · Flotillin-1 and Flotillin-2 (synonyms: reggie-2 and reggie-1) were originally described to be upregulated in regenerating axons of goldfish retinal ganglion cells after … dactylic hexameter 中文WebSep 26, 2024 · Part of flotillin complex. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Orthologous to human FLOT1 (flotillin 1). [provided by Alliance of Genome Resources, Apr 2024] Other designations. flotillin-1. GeneRIFs: Gene References Into … binnings pan american windows

"WebJul 3, 2024 · Non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) are associated with obesity. They are accompanied by increased levels of free cholesterol in the liver. Most free cholesterol resides within the plasma membrane. We assessed the impact of adding or removing free cholesterol on the function and … " - Flotillin complex

Flotillin complex

Flotillins/Cavatellins Are Differentially Expressed in Cells and Tissues an…

WebDec 13, 2002 · Plasma membrane association of both full-length flotillin and the green fluorescent protein-tagged PHB domain of flotillin is dependent on palmitoylation and … WebFeb 4, 2024 · Folkston-area complex now counts 3,018 beds near a city with about 4,400 residents. A corrections company has reached an agreement with local officials that …

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http://amigo.geneontology.org/amigo/term/GO:0016600 WebMay 28, 2024 · We then treated the cells with the cross-linker DSP and immunoprecipitated flotillin-1 with Flag antibody. Similar amounts of Flag signal and flotillin-2 were …

WebApr 4, 2024 · Antibodies targeting the flotillin-1/2 complex have been described in 1-2% of the patients in a recent study. Other candidate antigens as anoctamin-2 or neurofascin-155 have been previously described in multiple sclerosis patients, although their clinical relevance remains uncertain. Our study aims to analyse the frequency and clinical ... Webcomplex subunit μ2; Flot, flotillin; Tnr, transferrin receptor. (B–E) Cholesterol-regulated recycling of flotillin-1 is depen-dent on NPC1L1. (B and C) Flotillin-1-RFP was …

http://amigo.geneontology.org/amigo/term/GO:0016600#:~:text=A%20protein%20complex%20that%20contains%20flotillin-1%20and%20flotillin-2%2C,proteins.%20Flotillins%20associate%20into%20membrane%20microdomains%20resembling%20caveolae. WebApr 5, 2024 · Immunoglobulin G subclasses of anti-flotillin-1/2 antibodies were predominantly 1 and 3. We confirm that antibodies targeting the flotillin-1/2 complex are present in a subgroup of patients with ...

WebJan 1, 2024 · Flotillin-2 was originally cloned in 1994 by Schroeder et al. by immunoscreening of a human keratinocyte cDNA library using the monoclonal antibody ECS-1 against cultured keratinocytes. ... palmitoylation, and hydrophobic interaction. Flotillin-2 is mainly found in a hetero-oligomeric complex with its homologue flotillin-1, …

WebJul 14, 2024 · Loss of flotillins leads to a decrease in membrane fluidity that in turn leads to alterations in MreB dynamics and, as a consequence, in peptidoglycan synthesis. These alterations are reverted when membrane fluidity is restored by a chemical fluidizer. In vitro, the addition of a flotillin increases membrane fluidity of liposomes. dactyloa nasofrontalisWebOct 26, 2024 · Anaplasma phagocytophilum Hijacks Flotillin and NPC1 Complex To Acquire Intracellular Cholesterol for Proliferation, Which Can Be Inhibited with Ezetimibe … binning subdivisionsWebExtensive quantitative proteomic analysis allowing comparison of the isolated populations showed that several classically used exosome markers, like major histocompatibility complex, flotillin, and heat-shock 70-kDa proteins, are similarly present in all EVs. dactylische hexameterWebCadherin-1 or Epithelial cadherin (E-cadherin), (not to be confused with the APC/C activator protein CDH1) is a protein that in humans is encoded by the CDH1 gene. Mutations are correlated with gastric, breast, colorectal, thyroid, and ovarian cancers.CDH1 has also been designated as CD324 (cluster of differentiation 324). It is a tumor suppressor gene. dactylitis nursing care planWebTwo flotillin members have been described, flotillin-1 and flotillin-2. In addition to its colocalization with lipid rafts on the plasma membrane, flotillin-1 also has been found in compartments of the endocytic and autophagosomal pathways, such as recycling/late endosomes, the Golgi complex, and the nucleus (6,7). binning strips for drawersWebIn addition, co-immunoprecipitation experiments revealed that flotillins 1 and 2 are part of a stable hetero-oligomeric complex that contains both caveolins 1 and 2. However, protein levels of flotillin-1 and flotillin-2/ESA remain unchanged in response to oncogenic transformation of NIH 3T3 cells. dactylococcopsis spWebDec 15, 2014 · ABSTRACT. Flotillin 1 and 2 are ubiquitous and highly conserved proteins. They were initially discovered in 1997 as being associated with specific caveolin-independent cholesterol- and glycosphingolipid-enriched membrane microdomains and as being expressed during axon regeneration. Flotillins have a role in a large number of … binning property corporation